| 摘要 |
<p>Methods of identifying immunostimulatory DNA are provided, which methods include (i) detection of immunostimulatory DNA by formation of a complex between the DNA and isolated Replication Protein A (RPA) subunits; and (ii) down-regulation of CSF-1R expression by macrophages or macrophage cell cycle arrest. Also provided are immunostimulatory DNA agonists and antagonists.</p> |
