| 摘要 |
<p>A use of chitosan salt is disclosed, said salt having a deacetylation degree of 50 - 90 % and a molecular weight of 80,000 - 5,000,000 Da for the preparation of an aqueous ophthalmic formulation to be used as artificial tears having antimicrobial activity. The chitosan salt is used in an amount of 0.05 - 3 wt/v % based on the total aqueous ophthalmic formulation, said ophthalmic formulation having a viscosity of 10 - 500 mPa.s and a physiologically acceptable pH. The artificial tears obtained are particularly advantageous to treat dry eye syndrome and to prevent and cure infections or surinfections inherent to the treatment of dry eye.</p> |
