发明名称 ANTISENSE MODULATION OF NF-KAPPA-B P65 SUBUNIT EXPRESSION
摘要 <p>Antisense compounds, compositions and methods are provided for modulating the expression of NF-kappa-B p65 subunit. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NF-kappa-B p65 subunit. Methods of using these compounds for modulation of NF-kappa-B p65 subunit expression and for treatment of diseases associated with expression of NF-kappa-B p65 subunit are provided.</p>
申请公布号 WO0031111(A1) 申请公布日期 2000.06.02
申请号 WO1999US27762 申请日期 1999.11.23
申请人 ISIS PHARMACEUTICALS, INC.;BENNETT, C., FRANK;MONIA, BRETT, P.;COWSERT, LEX, M. 发明人 BENNETT, C., FRANK;MONIA, BRETT, P.;COWSERT, LEX, M.
分类号 A61K38/00;C12N15/113;(IPC1-7):C07H21/04;C12N15/85;C12Q1/68 主分类号 A61K38/00
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