发明名称 RETRO-INVERSION PEPTIDES THAT TARGET GASTRO-INTESTINAL TRACTTRANSPORT RECEPTORS AND USE THEREOF
摘要 Retro-invension forms of GIT targeting agents that target specific receptor sites in vivo and/or promote uptake of active agents and/or enhance active agent delivery across the GIT into the systemic circulation are provided. These retro-inverted peptides and compositions containing these retro-invert ed peptides can be used to deliver an active agent, such as a drug or a drug- containing nano- or microparticle for treatment of a condition in a subject in need of the drug, in vivo. Additionally, the invention provides antibodies which are capable of immunospecifically binding the retro-inverted peptides.
申请公布号 CA2349290(A1) 申请公布日期 2000.06.02
申请号 CA19992349290 申请日期 1999.11.19
申请人 ELAN CORPORATION, PLC 发明人 O'MAHONY, DANIEL JOSEPH
分类号 A61K9/14;A61K38/00;A61K45/00;A61K47/48;A61P3/10;A61P9/00;A61P9/04;A61P9/12;A61P19/10;A61P25/06;A61P35/00;C07K7/02;C07K7/08;C07K14/00;C07K16/44;(IPC1-7):C07K7/08;C07K19/00;A61K38/10;C07K16/18;A61K47/42 主分类号 A61K9/14
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