发明名称 Antibacterial and antifungal medicinal agent
摘要 The invention relates to the pharmaceutics, in particular to the stable agents with fungicidal and bactericidal action at the internal application thereof. Summary of the invention consists in the fact that the juglone (5-hydroxy-1,4-naphthoquinone) alcoholic solution additionally contains pharmaceutically acceptable polybasic organic hydroxyacids, for example, citric, malic or tartaric acid with the following component ratio, mass %: juglone 0,18...0,22 polybasic organic hydroxyacid 0,20...1,50 ethyl alcohol the rest. The presence of the polybasic hydroxyacid into the alcoholic solution in the indicated contents ensures a higher stability in storage (1,5...2,0 years) with the maintenance of the pharmacologic activity of the agent finished form, notwithstanding the water used for dilution, owing to the capacity of the given acids type to strongly complex with the alkali-earth metals ions present into the undistilled water. Claims: 2
申请公布号 MD1471(F1) 申请公布日期 2000.05.31
申请号 MD20000000026 申请日期 2000.01.14
申请人 INTREPRINDEREA MIXTA MOLDO-FRANCO-ROMANA "EUROFARM" SRL, 发明人 RUSU VASILE,;TIMCO GRIGORE,;CASIAN IGOR,;CASIAN ANA,;CHEPTANARU ZINAIDA,;VALICA VLADIMIR,;GAVRILUTA VADIM,;GHICAVAI VICTOR,;PRISACARI VIOREL,
分类号 A61K31/05;A61K31/12;A61P31/04;A61P31/10;(IPC1-7):A61K31/05;C07C46/10/ 主分类号 A61K31/05
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