发明名称 |
TRANSFORMED YEAST STRAINS AND THEIR USE FOR THE PRODUCTION OF MONOTERMINAL AND DITERMINAL ALIPHATIC CARBOXYLATES |
摘要 |
The present invention comprises a bioprocess for converting aliphatic compounds, of the form CH3(CH2)nCH3 where n = 4 to 20, to monoterminal and diterminal carboxylates using genetically-engineered organisms. This invention relates to a process for expressing alkane hydroxylating activity in genetically-engineered yeasts Pichia pastoris and Candida maltosa. In addition, the present invention describes a process to produce genetically transformed Candida maltosa strains that have enhanced cytochrome P450 activity and/or gene disruptions in the beta -oxidation pathway. |
申请公布号 |
EP1003881(A2) |
申请公布日期 |
2000.05.31 |
申请号 |
EP19980935806 |
申请日期 |
1998.07.20 |
申请人 |
E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED |
发明人 |
FALLON, ROBERT, D.;PAYNE, MARK, S.;PICATAGGIO, STEPHEN, K.;WU, SHIJUN |
分类号 |
C12N15/09;C12N1/15;C12N9/02;C12N15/53;C12P7/40;C12P7/44;C12R1/84 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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