Antibodies which bind to insect gut proteins and their use

摘要

PCT No. PCT/IB95/00497 Sec. 371 Date Dec. 20, 1996 Sec. 102(e) Date Dec. 20, 1996 PCT Filed Jun. 20, 1995 PCT Pub. No. WO96/00783 PCT Pub. Date Jan. 11, 1996Antibodies, monoclonal antibodies or fragments thereof which bind to brush border membrane vesicles of insect gut and the gene or genes which encode these proteins are provided. The monoclonal antibodies bind the gut of a target insect but do not bind to mammalian brush border membranes or to plant microsomes. The antibodies and the genes encoding them find use in constructing hybrid toxins for control of insect pests.