发明名称 |
Immunobiologically-active linear peptides and method of identification |
摘要 |
The present invention relates to identifying protein epitopes and more particularly to a novel method for identifying, determining the location, optimal length of amino acid residues and immunobiological potency of protein epitopes by applying a custom negative cosine function fit algorithm to a protein hydropathy scale. This fit analysis is supplemented with experimental immunobiological data. The amino acid sequence of the protein epitopes of the present invention exhibit a hydrophobic-hydrophilic-hydrophobic hydropathy pattern of an approximately fixed length in a given protein.
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申请公布号 |
US6070126(A) |
申请公布日期 |
2000.05.30 |
申请号 |
US19980097078 |
申请日期 |
1998.06.12 |
申请人 |
KOKOLUS, WILLIAM J. |
发明人 |
KOKOLUS, WILLIAM J.;FRITSCHE, HERBERT A.;JOHNSTON, DENNIS A. |
分类号 |
C07K14/00;(IPC1-7):C07K14/00 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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