发明名称 Polyol succinates and their pharmaceutical formulation
摘要 Compounds of formula (I) in which Y and Q are independently selected from hydrogen or alkyl groups, optionally substituted by 1-4 hydroxy or 1-4 R3O2CCH2CH2CO2- groups, where R3 is hydrogen or an alkyl group, and R1 and R2 are alkyl, and solvates and prodrugs thereof and the salts thereof in which R3 is a hydrogen atom. These compounds can be used in the treatment of diseases caused by or resulting in metabolic dysfunction and/or energy deprivation, such as diabetes, acute starvation, endotoxemia, sepsis, systemic inflammatory response syndrome and multiple organ dysfunction syndrome.
申请公布号 NZ332775(A) 申请公布日期 2000.05.26
申请号 NZ19970332775 申请日期 1997.06.04
申请人 LEO PHARMACEUTICAL PRODUCTS LTD AS LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB 发明人 BJORKLING, FREDRIK;MALAISSE, WILLY JEAN
分类号 A61K31/00;A61K31/225;A61P3/00;A61P3/10;C07C67/03;C07C69/40 主分类号 A61K31/00
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