| 发明名称 |
PENTAAZA-CYCLOPENTA[A]NAPHTHALENE DERIVATIVES AS LIGANDS FORGABAA ALPHA5 RECEPTORS |
| 摘要 |
A novel class of 1,2,3a,4,x-pentaaza-cyclopenta[a]naphthalenes (x=6, 7, 8 or 9) is described. The compounds have a high affinity for the GABAA .alpha.5 receptors and show inverse agonist activity thereat. The compounds are usefu l in therapy where cognition enhancement is required.
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| 申请公布号 |
CA2349488(A1) |
申请公布日期 |
2000.05.25 |
| 申请号 |
CA19992349488 |
申请日期 |
1999.11.03 |
| 申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
STERNFELD, FRANCINE;KULAGOWSKI, JANUSZ JOZEF;CURTIS, NEIL ROY |
| 分类号 |
A61K31/5025;A61P25/08;A61P25/28;C07D471/14;(IPC1-7):C07D471/14;C07D221/00;C07D237/00;C07D249/00;A61K31/50 |
主分类号 |
A61K31/5025 |
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