METHOD FOR GRAFTING SUBSTITUTED DIFLUOROMETHYLE GROUP

摘要

PURPOSE: A process is provided for grafting a substituted difluoromethyl group on a compound containing at least one electrophilic function. CONSTITUTION: A method for grafting a substituted difluoromethyl group is used for forming in particular sulphinic or fluorine containing sulphonic acids. The method comprises the following steps: i) bringing said compound containing at least one electrophilic function in the presence of one nucleophilic reagent containing: a) a fluorocarboxylic acid of formula Ea-CF2-COOH in which Ea represents an electroattracting atom or group, at least partly salified by one organic or mineral cation, and b) a polar aprotic solvent; and ii) exposing the reaction medium to the action of microwaves.