PHARMACEUTICAL COMPOSITION CONTAINING TETRAHYDROISOQUINOLINE COMPOUND

摘要

PURPOSE: Provided is a novel application of tetrahydroisoquinoline compound for a pharmaceutical composition, which could be used as a treatment for cardiac insufficiency, thrombosis, sepsis and/or disseminated intravascular coagulation(DIC). CONSTITUTION: Provided is a novel use of tetrahydroisoquinoline compounds which showcardiotonic and hypotensor effects, and suppression effects of platelet aggregation and iNOS(inducible NO syntheas) simultaneously in particular, a pharmaceutical composition comprising one or more of 1-alpha-naphthylmethy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, and 1-beta-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoloine described in formula 1 and formula 2 respectively as available components is provided. The pharmaceutical compositions used as treatments for cardiac insufficiency such as infarction, chromic inflammation, hypertension, arteriosclerosis or congestive heart failure, thrombosis, sepsis and/or disseminated intravascular coagulation(DIC).