COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS

摘要

A method of alleviating a pain state not associated with a cough condition is provided which comprises administering a cyclooxygenase-2 inhibitor and a centrally active analgesic selected from the group consisting of a narcotic analgesic selected from the group consisitng of codeine and hydrocodone; an agonist-antagonist analgesic and tramadol. A method and analgesic composition therefor is also provided for treating all pain states which comprises administering a cyclooxygenase-2 inhibitor and a centrally acting analgesic selected from the group consisting of a narcotic analgesic other than codeine and hydrocodone; an agonist-antagonist analgesic and tramadol.