IL-8 RECEPTOR ANTAGONISTS

摘要

PURPOSE: Novel compounds of formula (I), pharmaceutical compositions and their use in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8) is provided. CONSTITUTION: A method of the treatment of disease state mediated by chemokine combining to Interleukin-8 (IL-8) or β accepter comprises administering effective amount of compounds of formula (I), pharmaceutical compositions. Particularly, the chemokine is Interleukin-8.