发明名称 |
3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives |
摘要 |
<p>3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives represented by general formula (1) and their pharmacologically acceptable salts having a selective beta 2-adrenergic receptor stimulating effect with a relieved burden on the heart such as a frequent pulse. In said formula, A represents lower alkylene; B represents amino, di(lower alkyl)amino or 3- to 7-membered alicyclic amino optionally containing oxygen in the ring; n is an integer of 1 or 2; the carbon atom marked with "*" means a carbon atom or the R- or S- configuration or a mixture thereof; and the carbon atom marked with "(S)" means a carbon atom of the S-configuration. These compounds are useful as a preventive for threatened abortion/premature birth, a bronchodilator and a pain-relieving and lithagogue agent in ureterolithiasis. <CHEM></p> |
申请公布号 |
SG72727(A1) |
申请公布日期 |
2000.05.23 |
申请号 |
SG19970000355 |
申请日期 |
1997.02.17 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
KITAZAW MAKIO;OKAZAKI KOSUKE;TAMAI TETSURO;SAITO MASARU;TANAKA NOBUYUKI;KOBAYASHI HIROAKI;KIKUCHI KEN;MURANAKA HIDEYUKI |
分类号 |
C07C235/06;C07D295/185;(IPC1-7):C07C235/20;A61K31/535;A61K31/445;A61K31/40;A61K31/16 |
主分类号 |
C07C235/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|