| 摘要 |
PCT No. PCT/FR96/01200 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1988 PCT Filed Jul. 30, 1996 PCT Pub. No. WO97/05255 PCT Pub. Date Feb. 13, 1997Novel helper vectors are provided for complementing defective recombinant viral vectors, characterized in that they are provided with recombination sequences recognized by a recombinase. A complementation cell expressing the recombinase, and a method for preparing recombinant viral vectors as infectious viral particles for transferring and expressing genes of interest in a host organism or cell, are also provided. The invention is particularly suitable for use in gene therapy, especially in humans.
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