发明名称 Method for producing a rapidly dissolving dosage form
摘要 A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix which will serve as the dosage form matrix is produced. In a second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
申请公布号 US6066337(A) 申请公布日期 2000.05.23
申请号 US19980111113 申请日期 1998.07.06
申请人 THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA AND JANSSEN PHARMACEUTICA, INC. 发明人 ALLEN, LOYD V.;WANG, BINGNAN;DAVIES, JOHN DESMOND
分类号 A61K9/00;A61K9/20;(IPC1-7):A61K9/14;A61K9/16;A61K9/46 主分类号 A61K9/00
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