摘要 |
PROBLEM TO BE SOLVED: To obtain an antisense nucleic acid compound inhibiting the genes encoding p300 and CBP and useful for medicines for treating and diagnosing leukemia, or the like, reagents for analyzing the functions of genes, or the like, by disposing a specific base sequence. SOLUTION: This antisense nucleic acid compound for inhibiting the expression of p300 or CBP has base sequences of formulas I to V or their substantially same base sequences. The antisence nucleic acid compound for inhibiting the expression of the p300 or CBP preferably comprises a natural type or phosphothioate type oligodeoxyribonucleotide. |