发明名称 |
4-phenyl-3-substituted 1,4-dihydropyridine esters |
摘要 |
4-Phenyl-3-substituted 1,4-dihydropyridine esters are prepared by reaction of benzaldehydes with ketoesters and enamines, if appropriate with isolation of the ylidene intermediate products, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols. The new 4-phenyl-3-substituted 1,4-dihydropyridine esters can be employed as active compounds in medicaments for the treatment of the central nervous system, in particular as cerebral therapeutics.
|
申请公布号 |
US6066655(A) |
申请公布日期 |
2000.05.23 |
申请号 |
US19970988114 |
申请日期 |
1997.12.10 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
MEIER, HEINRICH;HARTWIG, WOLFGANG;JUNGE, BODO;SCHOHE-LOOP, RUDOLF;GAO, ZHAN;SCHMIDT, BERNARD;DE JONGE, MAARTEN;SCHUURMAN, TEUNIS |
分类号 |
A61K31/4427;A61K31/455;A61P9/08;A61P25/24;A61P25/26;A61P25/28;C07D211/90;C07D401/12;(IPC1-7):C07D211/86 |
主分类号 |
A61K31/4427 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|