发明名称 Method of detecting metastatic thyroid cancer
摘要 This invention provides a method of detecting metastatic thyroid cancer in a subject which comprises detecting circulating thyroid cells in a bodily fluid sample of the subject by obtaining an appropriate nucleic acid sample from the bodily fluid sample of the subject; and determining whether the nucleic acid sample contains a marker sequence. Specifically, this invention provides wherein the marker sequence is mRNA corresponding to the reverse transcript of DNA encoding thyroglobulin. Also, this invention provides wherein the marker sequence is mRNA corresponding to the reverse transcript of DNA encodes thyroid peroxidase. This invention further provides a test kit for performing the above-described method.
申请公布号 US6066449(A) 申请公布日期 2000.05.23
申请号 US19970840551 申请日期 1997.04.15
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 DITKOFF, BETH ANN;CHABOT, JOHN A.;FEIND, CARL R.;LOGERFO, PAUL
分类号 C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C07H21/02 主分类号 C12Q1/68
代理机构 代理人
主权项
地址