发明名称 Cycloheximide derivatives which influence the regeneration of neural tissue
摘要 The invention relates to novel compounds of general formula (1) in which n represents a whole number ranging from 1 to 20; each R<12> independently represents a hydrogen atom or an alkyl radical; R<1> is selected from an oxygen atom, from a sulfur atom or from the groups NR<2>, NOR<2> and N-NR<2>R<3>; R<7> represents a radical -OH, OR<9>, -OC(O)R<9>, -OC(S)R<9>, -OC(O)NHR<9>, -OC(S)NHR<9> or O(CHR<12>)nR<10>, and; R<10> represents a radical -NHR<2>, -NR<2>R<3>, -C(O)OR<2>, -C(S)OR<2>, -C(O)NR<2>R<3>, -CN, NR<2>C(O)NR<2>R<3>, -OC(O)NR<2>R<3>, -NR<2>C(S)NR<2>R<3>, -OC(S)NR<2>R<3> or C(O)NHR<11>. The inventive compounds are capable of influencing the regeneration of neural tissue. The invention also relates to pharmaceutical compositions containing compounds of this type and to the use thereof for treating defective neural tissue.
申请公布号 AU1157900(A) 申请公布日期 2000.05.22
申请号 AU20000011579 申请日期 1999.10.29
申请人 MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.;HANS-KNOLL-INSTITUT FUR NATURSTOFF-FORSCHUNG E.V. 发明人 GUNTER FISCHER;GERHARD KULLERTZ;CLAUDIA CHRISTNER;RALF WYRWA;SUSANNE GRABLEY;RALF THIERICKE
分类号 A61K38/00;C07D211/88;C07K5/06;C07K5/078 主分类号 A61K38/00
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