<p>The present invention relates to a vaccine containing at least one immunogen and an adjuvanting amount of B subunits of heat-labile enterotoxin characteristic of E. coli isolated from a non-human source. This vaccine is particularly suitable for induction of a protective response against said immunogen upon mucosal (e.g. intra-nasal) administration.</p>
申请公布号
NO20002613(D0)
申请公布日期
2000.05.22
申请号
NO20000002613
申请日期
2000.05.22
申请人
DUPHAR INTERNATIONAL RESEARCH BV, PATENT DEPT;UNIVERSITEIT VAN GRONINGEN
发明人
AGSTERIBBE, ETIENNE;BRANDS, RUDI;HAAN, LOLKE DE;SCHARRENBURG, GUSTAAF JOHAN MARIE;VERWEIJ, WILLEM RONALD;WILSCHUT, JAN CHRISTIAAN