发明名称 |
NEW FAMILY OF MAMMALIAN POTASSIUM CHANNELS, THEIR CLONING AND THEIR USE, ESPECIALLY FOR THE SCREENING OF DRUGS |
摘要 |
This invention relates to a new member of a recently recognized TWIK potassium transport channels, herein designated as TASK2. TASK2 is a unique potassium transport channel which is regulated by external pH and predominantly expressed in kidney and epithelial tissues. The invention relates to various constructs of TASK2 for the production of TASK2 and their uses for diagnostic tests and screening methods to identify compounds that modulate potassium transport.
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申请公布号 |
WO0027871(A2) |
申请公布日期 |
2000.05.18 |
申请号 |
WO1999IB01886 |
申请日期 |
1999.11.09 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS |
发明人 |
DUPRAT, FABRICE;LESAGE, FLORIAN;LAZDUNSKI, MICHEL |
分类号 |
C07K14/705;(IPC1-7):C07K14/00 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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地址 |
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