A plastic pipette tip (32) easily and firmly mountable on and easily ejectable from a pipette mounting shaft (34) of a pipette (10) by application of relatively small axial mounting and ejection forces of about six and three (3) pounds respectively. The pipette tip includes a tubular proximal portion (30) comprising (i) a frusto-conical open upper end portion (40) having an inner diameter at its upper end greater than the diameter of a mounting shaft (34) of the pipette to which the pipette tip is to be mounted, (ii) a hollow mid-portion (42) and (iii) an annular sealing region (46) at a junction of the open end and mid-portions. The annular sealing region has an inner diameter less than "x" and is designed to engage a lower end of a sealing zone (36) of the mounting shaft to stretch radially outward as the mounting shaft is guided and stably oriented in the proximal portion thereby creating a fluid tight seal between the sealing zone and the sealing region.
