Rekombinante Glycoproteine, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und ihre Verwendung

摘要

The invention relates to novel recombinant glycoproteins that act as messenger substances, signaling substances, promoters, stimulators and initiators in a multitude of ways in the animal, especially human, circulation system. The invention also relates to a method for the production thereof, pharmaceutical agents containing said glycoproteins and the use thereof. The invention more particularly relates to novel recombinant human glycoproteins (rh glycoproteins), preferably novel rh differentiation factors, especially rh erythropoietin; novel rh growth factors, especially rh CSF (colony stimulating factor), rh GMCSF (granulocyte monocyte stimulation factor); novel rh thrombolytic agents, especially rh tPA (tissue plasminogen activator) and rh urokinase; novel rh thromboprophylactic agents, especially rh antithrombin III; novel rh coagulation factors, especially rh factor VIII and rh factor IX; novel rh interferons, especially rh alpha , beta and gamma interferons; and novel rh interleukins, especially rh IL-2, IL-15, IL-16 and IL-17. The invention further relates to a method for the production of said substances, pharmaceutical agents containing them and to the use thereof.