| 发明名称 |
A METHOD OF TREATING TUMORS USING FAS-INDUCED APOPTOSIS |
| 摘要 |
The present invention provides a method of killing a Fas+ tumor cell comprising introducing into a second tumor cell a nucleic acid encoding a Fa s ligand (FasL), whereby the second tumor cell expresses the nucleic acid thereby producing FasL, and whereby interaction of the Fas+ tumor cell with the second tumor cell expressing FasL causes the Fas+ tumor cell to undergo apoptosis, thereby killing the Fas+ tumor cell.
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| 申请公布号 |
CA2347847(A1) |
申请公布日期 |
2000.05.18 |
| 申请号 |
CA19992347847 |
申请日期 |
1999.11.05 |
| 申请人 |
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT |
发明人 |
NORRIS, JAMES S.;DONG, JIAN-YUN |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;A61P35/00;C07K14/705;C12N5/10;C12N15/62;C12N15/861;(IPC1-7):C12N15/86;C07K14/435;C12N15/63 |
主分类号 |
C12N15/09 |
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