发明名称 Method of treating a tumor
摘要 In accordance with the present invention there is provided a method of treating a mammal having a solid tumor, the method comprising: a) administering to the mammal an effective amount of 3-amino-1,2,4-benzotriazine 1,4-dioxide; b) administering to the mammal an effective amount of paclitaxel; and c) administering to the mammal an effective amount of a platinum complex. The method provides unexpected synergistic efficacy. The invention further provides a kit for treatment of a mammalian tumor comprising 3-amino-1,2,-benzotriazine 1,4-dioxide, paclitaxel and a platinum complex.
申请公布号 US6063780(A) 申请公布日期 2000.05.16
申请号 US19980031692 申请日期 1998.02.27
申请人 SANOFI-SYNTHELABO INC. 发明人 DEXTER, DANIEL L.;JUNIEWICZ, PAUL E.;RAKE, JAMES B.;VON HOFF, DANIEL D.
分类号 A61K31/28;A61K31/335;A61K31/337;A61K31/53;A61K31/555;A61K33/24;A61P35/00;(IPC1-7):A61K31/53 主分类号 A61K31/28
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