发明名称 |
Heterocyclic topoisomerase poisons |
摘要 |
The invention provides a topoisomerase poison of formula I: wherein R1-R8 have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof.
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申请公布号 |
US6063801(A) |
申请公布日期 |
2000.05.16 |
申请号 |
US19980023147 |
申请日期 |
1998.02.12 |
申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
LAVOIE, EDMOND J.;KIM, JUNG SUN;RANGARAJAN, MEERA;LIU, LEROY FONG |
分类号 |
A61K31/4184;A61P31/10;A61P35/00;A61P43/00;C07D235/18;C07D235/26;C07D235/28;C07D235/30;C07D491/04;(IPC1-7):A61K31/418;C07D238/26;C07D235/24 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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