| 摘要 |
Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and a complexing ligand having the general formula Ia, Ib or Ic, (see formula I) wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
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| 申请人 |
LINDER, KAREN;NUNN, ADRIAN D.;NOWOTNIK, DAVID P.;RAMALINGAM, KONDAREDDIAR;DI ROCCO, RICHARD J.;RUMSEY, WILLIAM L.;PIRRO, JOHN P. |
发明人 |
LINDER, KAREN;NUNN, ADRIAN D.;NOWOTNIK, DAVID P.;RAMALINGAM, KONDAREDDIAR;DI ROCCO, RICHARD J.;RUMSEY, WILLIAM L.;PIRRO, JOHN P. |
