Process for producing spherical fine particles containing drug

摘要

The present invention discloses an efficient preparation method of spherical fine particles containing a drug for an easily-swallowed, controlled-release preparation comprising the production of drug-containing spherical fine particles (mean particle size: 60-200 mu m) by adding a binder solution to a mixture containing an excipient powder having the property of retaining solvent (and preferably having a mean length of the long axis of 40 mu m or less) and a drug powder (preferably having a mean length of the long axis of 50 mu m or less), followed by high-speed mixing granulation.