| 摘要 |
The invention concerns the fields of biology and immunology. It concerns membrane vesicles comprising molecules, in particular antigenic molecules, with predetermined structure, and their uses, More particularly, it concerns vesicles (exosomes) comprising recombinant molecules of the major histocompatibility complex, and their use as immunogen or for diagnostic and therapeutic purposes. The invention also concerns methods for producing said vesicles, genetic constructs, cells and compositions, useful for implementing said methods.
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