CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS

摘要

The invention relates to compounds having formula (I), wherein R1, R2, R3, R 4, R5, R7, R8, R11, Z, m and n have the meaning cited in claim 1, and to the physiologically acceptable salts and solvates which can be used as integrin inhibitors, especially in the prophylaxis and treatment of circulatory diseases, in case of thrombosis, myocardial infarction, coronary heart diseases, arteriosclerosis, osteoporosis, pathologic processes caused or propagated by angiogenesis and in tumor therapy.