DNA plasmid vaccine for immunization of animals against BVDV

摘要

The present invention relates to a DNA plasmid vaccine for immunization of animals against BVDV which comprises at least a mammalian expression vector having a DNA sequence encoding at least one BVDV immunogenic protein or fragment thereof which is selected from the group consisting of BVDV major glycoprotein gp53/E2, p20 (Npro), p14/C, gp48/E0, gp25/E1 and p80/NS3 proteins, the immunogenic protein is operably linked downstream from a suitable promoter for its expression, whereby inducing a BVDV-specific antibody responses.