PHOSPHATE-BINDING POLYMER PREPARATIONS

摘要

Tablets which contain phosphate-binding polymers having an average particle size of 400 mu m or less, containing particles of 500 mu m or less in particle size at a ratio of at least 90 % and showing a moisture content of 1 to 14 % and crystalline cellulose and/or hydroxypropylcellulose with a low degree of substitution; and a process for producing the same. These tablets have a high active component content and an excellent ability to bind to phosphates and are quickly disintegrated in an acidic to neutral region while being little affected by stirring strength. Thus, they are excellent preparations capable of lessening changes in bioavailability depending on pH value.