发明名称 |
Interstitial fluid monitoring |
摘要 |
The present invention provides an improved method of measuring analytes in bodily fluids without the use of a sharp. The method having the steps of irradiating the skin of a patient by focused pulses of electromagnetic energy emitted by a laser. By proper selection of wavelength, energy fluence, pulse temporal width and irradiation spot size, the pulses precisely irradiate the skin to a selectable depth, without causing clinically relevant damage to healthy portions of the skin. After irradiation, interstitial fluid is collected into a container or left on the skin. The interstitial fluid is then tested for a desired analyte to approximate the analyte concentration in other bodily fluids. Alternatively, after the forced formation of a microblister, the epidermis covering the microblister is lysed and the interstitial fluid is subsequently collected and tested.
|
申请公布号 |
US6056738(A) |
申请公布日期 |
2000.05.02 |
申请号 |
US19970955982 |
申请日期 |
1997.10.22 |
申请人 |
TRANSMEDICA INTERNATIONAL, INC. |
发明人 |
MARCHITTO, KEVIN S.;FLOCK, STEPHEN T. |
分类号 |
A61B5/145;A61B10/00;A61B17/00;A61B17/34;A61B18/00;A61B18/20;A61B19/00;A61M37/00;A61N5/06;(IPC1-7):A61N5/00 |
主分类号 |
A61B5/145 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|