发明名称 Amidite derivatives and oligonucleotide derivatives
摘要 PCT No. PCT/JP96/00868 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Mar. 29, 1996 PCT Pub. No. WO96/30386 PCT Pub. Date Oct. 3, 1996The present invention provides a compound of general formula (I): wherein X represents group (II) or (III): wherein Y represents a leaving group and Z represents an oligonucleotide. The compound can specifically transfer oligonucleotides to cells which specifically recognize a specified saccharide construction. Accordingly, the compound can be used as an antiviral agent or an antitumor agent.
申请公布号 US6057431(A) 申请公布日期 2000.05.02
申请号 US19970930677 申请日期 1997.12.22
申请人 DRUG DELIVERY SYSTEM INSTITUTE, LTD. 发明人 ISHIHARA, HIROSHI;KAWAGUCHI, TAKAYUKI;IKEDA, MASAHIRO;NAKAMOTO, KAZUTAKA;SASAKI, ATSUSHI
分类号 C07H21/00;(IPC1-7):C07H21/02;C07H19/00;C07H1/00 主分类号 C07H21/00
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