| 发明名称 |
PROCESSES FOR PREPARING AI-MILANO APOLIPOPROTEIN DIMER |
| 摘要 |
The invention relates to two processes for preparing AI-Milano apolipoprotein dimer by recombinant technology, as an intracellular fusion protein in Escherichia Coli and by secreting the AI-Milano monomer and dimer in the bacteria culture medium in an Escherichia Coli expression system The AI-Milano apolipoprotein dimer is used in the form of compositions or for preparing a drug for preventing the cardiovascular diseases, atheriosclerosis, myocardium infarction, for treating thrombosis and stimulating fibrinolysis
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| 申请公布号 |
RO115636(B1) |
申请公布日期 |
2000.04.28 |
| 申请号 |
RO19930001116 |
申请日期 |
1992.12.11 |
| 申请人 |
KABI PHARMACIA AB, UPPSALA |
发明人 |
SIRTORI CESARE;FRANCESCHINI GUIDO;ABRAHMENSEN LARS;HOLMGREN ERIK;LAKE MATS;NILSSON BJORN;CHMIELEWSKA JOANNA;LIND PETER |
| 分类号 |
C12P21/00;A61K35/16;A61K38/00;A61K38/16;A61K38/17;A61K38/33;A61P3/06;A61P7/02;A61P9/00;A61P9/10;C07K1/00;C07K1/18;C07K1/20;C07K14/775;C07K19/00;C12N15/16;C12P21/04;(IPC1-7):C07K15/16;A61K37/02 |
主分类号 |
C12P21/00 |
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