The present invention relates to compositions and methods for delivery of nucleic acids. In particular, the invention provides a polymeric delivery formulation including a nucleic acid to be transfected into a host cell, formulated in a biodegradable polymer having phosphorous-based linkages.
申请公布号
WO9965531(A9)
申请公布日期
2000.04.27
申请号
WO1999US13853
申请日期
1999.06.18
申请人
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;MAO, HAI-QUAN;LIN, KEVIN, Y.;HENDRIKS, BART, S.;LEONG, KAM, W.;HALLER, MICHAEL
发明人
MAO, HAI-QUAN;LIN, KEVIN, Y.;HENDRIKS, BART, S.;LEONG, KAM, W.;HALLER, MICHAEL