GENE TRANSFER CELL SHEET AND PROCESS FOR PREPARING THE SAME

摘要

A gene transfer cell sheet consisting of a plural number of layers of mucosal epithelial cells having a gene transferred thereinto. By selecting the subject gene, this sheet can elevate the taking efficiency upon a living body and the product of the thus transferred gene can be formed over a long time after the transfer. Owing to these characteristics, this sheet is usable as a graft having a high taking efficiency or as a carrier in gene therapy. Moreover, the mucosal epithelial cells constituting the sheet are undifferentiated cells into which a subject gene can be easily transferred. Thus, the sheet can be readily prepared.