Methods and adjuvants for stimulating mucosal immunity

摘要

The invention relates to methods for inducing mucosal immunity to an antigen and provides oligonucleotide adjuvants effective in stimulating such immunity against antigens. The adjuvants provided by the invention have little toxicity, are relatively simple to manufacture as compared to cholera toxin and other mucosal adjuvants, and possess the additional advantages of biasing the host immune response toward the Th1 phenotype.