| 发明名称 |
Mage-a3 peptides presented by hla class ii molecules |
| 摘要 |
The invention describes HLA class II binding peptides encoded by the MAGE-3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-3 gene. |
| 申请公布号 |
AU6042099(A) |
申请公布日期 |
2000.04.26 |
| 申请号 |
AU19990060420 |
申请日期 |
1999.09.15 |
| 申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH;VRIJE UNIVERSITEIT BRUSSEL |
发明人 |
PASCAL CHAUX;VINCENT STROOBANT;THIERRY BOON-FALLEUR;PIERRE VAN DER BRUGGEN;ERWIN S. SCHULTZ;JACQUES VAN SNICK;BERNARD LETHE;KRIS THIELEMANS;JURGEN CORTHALS;CARLO HEIRMAN |
| 分类号 |
C12N15/09;A61K35/14;A61K35/26;A61K38/00;A61K39/00;A61K45/00;A61P35/00;A61P37/04;C07K7/06;C07K7/08;C07K14/47;C07K14/705;C07K14/82;C07K16/30;C07K16/32;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N15/12;C12P21/08;C12Q1/02;C12R1/91;G01N33/53 |
主分类号 |
C12N15/09 |
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