发明名称 |
NOVEL NITROXYL COMPOUNDS AND DRUGS AND REAGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT |
摘要 |
<p>Nitroxyl compounds represented by general formula (I) which are usable in acquiring information about active oxygen or in vivo free radicals as biological images such as magnetic resonance images or magnetoencephalograms, wherein A represents hydrogen or -L-(CH2)n-OCOR (wherein L represents -COO- or -alkylene-COO-; and R represents C1-4 alkyl); R1, R2, R3, and R4 represent each C1-4 alkyl; and n is a number of from 1 to 4. Drugs and reagents containing the above compounds are usable in preventing, treating or diagnosing ischemic diseases, digestive diseases, cancer, cranial nervous diseases accompanied by nerve degeneration, inflammation, cataracts, or drug-induced organopathy. <CHEM></p> |
申请公布号 |
EP0995740(A1) |
申请公布日期 |
2000.04.26 |
申请号 |
EP19980929708 |
申请日期 |
1998.06.26 |
申请人 |
DAIICHI RADIOISOTOPE LABORATORIES, LTD. |
发明人 |
UTSUMI, HIDEO;SANO, HIROAKI;NARUSE, MASAICHI;IGARASHI, TAKASHI;OI, TETSUO |
分类号 |
A61K49/00;A61K49/20;C07D207/46;C07D211/94;(IPC1-7):C07D207/46;A61K31/40;A61K51/04 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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