发明名称 Ligands for sigma receptors and their therapeutical applications
摘要 2-arylalkenyl-azacycloalkane derivs. of formula (I) are sigma receptors. (I), their isomers and acid addn. salts and their derivs. in which an atom is replaced by a radioisotope, are new. Ar = aryl or heteroaryl (opt. mono-, di- or tri-substd.); m = 1 or 2; n = 1 - 3; R = phenyl (opt. substd.) or 3-7C cycloalkyl.
申请公布号 EP0995436(A2) 申请公布日期 2000.04.26
申请号 EP19990114215 申请日期 1994.12.09
申请人 PARKE-DAVIS 发明人 CALVET, ALAIN;JACOBELLI, HENRY;JUNIEN, JEAN-LOUIS;RIVIERE, PIERRE;ROMAN, FRANCOIS JOSEPH
分类号 A61K31/00;A61K31/40;A61K31/4025;A61K31/445;A61K31/451;A61K31/4535;A61P1/00;A61P1/04;A61P1/12;A61P25/18;A61P43/00;C07D207/06;C07D207/08;C07D211/14;C07D495/06;(IPC1-7):A61K31/00;A61K31/402;A61K31/453 主分类号 A61K31/00
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