发明名称 Interleukin-1 receptor antagonist beta (IL-1ra beta )
摘要 IL-1ra beta polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1ra beta polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, septicemia, arthritis, inflammatory bowel disease, graft vs. host disease, autoimmunity, stroke, cardiac ischemia, acute respiratory disease syndrome (ARDS), psoriasis, restenosis, traumatic brain injury, AIDS, cachexia, allergy, parasite infection, allergic rhinitis, allergic asthma, atopic dermatitis, allergic inflammatory diseases, and delayed hypersensitivity., among others, and diagnostic assays for such conditions.
申请公布号 US6054559(A) 申请公布日期 2000.04.25
申请号 US19980069619 申请日期 1998.04.29
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 YOUNG, PETER R.
分类号 G01N33/50;A61K38/00;A61K38/28;A61K45/00;A61K48/00;A61P11/02;A61P11/06;A61P29/00;A61P37/08;A61P43/00;C07K14/54;C07K14/545;C07K16/24;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/25;C12P21/02;C12Q1/02;C12Q1/68;G01N33/566;G01N33/68;(IPC1-7):C07K14/52 主分类号 G01N33/50
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