发明名称 |
Anti-gram-positive bacterial methods and materials |
摘要 |
The present invention relates to methods of treating gram-positive bacterial infections by administration of a BPI protein product alone, or in combination with an antibiotic. BPI protein product alone has a bactericidal or growth inhibitory effect on selected gram-positive organisms. BPI protein product also increases the susceptibility of gram-positive organisms to antibiotics and can even reverse resistance of gram-positive organisms to antibiotic.
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申请公布号 |
US6054431(A) |
申请公布日期 |
2000.04.25 |
申请号 |
US19980119263 |
申请日期 |
1998.07.20 |
申请人 |
XOMA CORPORATION |
发明人 |
HORWITZ, ARNOLD;LAMBERT, JR., LEWIS H.;LITTLE, II, ROGER G. |
分类号 |
C12N15/09;A01N37/18;A61K31/70;A61K38/00;A61K38/17;A61K45/06;A61P3/00;A61P31/04;C07H21/04;C07K14/47;C12P21/02;(IPC1-7):A61K38/00;A61K31/43;C07K1/00 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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