MICROSPHERES CONTAINING BIOLOGICALLY-ACTIVE COMPONENTS, PROCESSES FOR THE PREPARATION AND USES

摘要

Novel smooth surface microspheres having a diameter of between 1 .mu.m to 100 .mu.m are provided herein. Such microspheres comprise a particular biologically-active molecule, namely, a high molecular weight molecule of a proteic nature or of a glycosphingolipid nature and an ester of hyaluronic acid or mixtures of the esters of hyaluronic acids. In these smooth surface microspheres, the biologicallyactive molecule is adhered to the ester of hyaluronic acid. Such smooth surface microspheres have utility for the controlled release of the biologically-active molecule.