| 摘要 |
PURPOSE: New peptides derived from the MAGE-2 molecule and binding to HLA-A 0201 molecules are provided which induce CTL proliferation when complexed to their HLA-A 0201 partner molecules, to be used in various ways such as an antigen. CONSTITUTION: A cytolytic T cell clone is isolated which is specific for a complex of an HLA-A2 molecule and one of SEQ ID NO. 3, SEQ ID NO. 5, and SEQ ID NO. 9. A method for inducing cytolytic T cells in a subject comprises administering an amount of at least one of SEQ ID NO. 3, SEQ ID NO. 5, and SEQ ID NO. 9, to a subject who presents HLA-A2 molecule on cells, in an amount sufficient to provoke cytolytic T cell proliferation to complexes of HLA-A2 and one of SEQ ID NO. 3, SEQ ID NO. 5, and SEQ ID NO. 9. |
