| 摘要 |
A process for the purification and crystallization of riboflavin comprises dissolving needle-shaped riboflavin of the stable modification A in an aqueous mineral acid solution at a temperature not exceeding about 30.degree.C with intensive intermixing, adding active charcoal to the resulting solution, after adsorption of the dissolved impurities from the solution on the active charcoal subjecting the medium containing the active charcoal to a counter-current filtration over a ceramic membrane having a pore size of about 20 to about 200 nm, treating the resulting filtrate with a five- to ten-fold amount (vol./vol.) of water at a temperature not exceeding about 30.degree.C and separating the resulting precipitated, spherical crystals of riboflavin by centrifugation or filtration. If desired, the thus-obtained spherical crystals of riboflavin can be washed with water and subsequently dried. The thus-purified and crystallized riboflavin is suitable for pharmaceutical and foodstuff applications.
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