PURIFICATION OF BIPHENYL-BASED OPTICALLY ACTIVE COMPOUND

摘要

PROBLEM TO BE SOLVED: To improve an optical purity and to obtain a compound having a high optical purity by purifying (+)-4-(2-methylbutanoyl)biphenyl or (+)-4-(2- methylbutyl)biphenyl by a simple operation. SOLUTION: In recrystallizing optically active 4-(2-methylbutanoyl)biphenyl or optically active 4-(2-methylbutyl)biphenyl, an organic solvent mixable with water at any ratio is used as a good solvent, water is used as a poor solvent and recrystallization is carried out at <=20 deg.C to purify the biphenyl-based optically active compound.