发明名称 |
Production of solid drug forms |
摘要 |
Solid drug forms are produced by mixing and melting at least one pharmacologically acceptable polymeric binder and at least one pharmaceutical active ingredient, with or without conventional pharmaceutical additives, in the absence of a solvent to give a plastic mixture and shaping the mixture to the required drug form by extrusion, where the shaping takes place in two steps, with the extrudate being broken into shaped articles in a first step, and these shaped articles being rounded off in a second step in the plastic state.
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申请公布号 |
US6051253(A) |
申请公布日期 |
2000.04.18 |
申请号 |
US19970886286 |
申请日期 |
1997.07.01 |
申请人 |
BASF AKTIENGESELLSCHAFT |
发明人 |
ZETTLER, HANS DIETER;SCHIESSL, MICHAEL;BREITENBACH, JOERG;ROSENBERG, JOERG |
分类号 |
A61J3/10;A61J3/06;A61K9/20;B30B11/22;(IPC1-7):A61K9/20 |
主分类号 |
A61J3/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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